Goethe-University. Frankfurt, Germany

The hosts of this seminar are Maribel Parra and Oriol de Barrios.

Rolf Marschalek has studied biology/biochemistry at the University of Erlangen/Nuremberg and completed his PhD in 1989. During his post-doc period, he worked on "jumping genes" and on the molecular basis of cellular transcription. In 1992, he became assistant professor at the newly founded Institute of Genetics in Erlangen, where he began his work on MLL/KMT2A translocation and the pathogenesis of high-risk leukemia. In 2000, he was appointed as full professor at the Institute of Pharmaceutical Biology of the Goethe-University in Frankfurt/Main. In 2005, he founded the Diagnostic Center of Acute Leukemia (DCAL), where he and his colleague Dr. Claus Meyer have since discovered over 100 new cancer genes fused to the MLL/KMT2A gene (MLL recombinome). Rolf Marschalek's group is currently working on new therapeutic strategies for juvenile t(4;11) high-risk leukemia.

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