March 27, 2026 (12:00)
“Microbial viability drives immunometabolic responses in macrophages"
Dr Johan Garaude
INSERM, University of Bordeaux
The host of this seminar is Laura Belver.
Johan Garaude got his Ph.D. in Moleclular Endocrinology in 2007 from the University of Montpellier, France, for his work on mitogen-activated protein kinases (MAPK) and activating-protein 1 (AP-1) in leukemogenesis and T cell activation under the supervision of Dr. Martin Villalba. In 2008, he joined the laboratory of Dr. Julie Magarian Blander at the Mount Sinai School of Medicine in New York where he investigated how a dual ligand for innate immune receptors can be used to generate potent antitumor immune responses and contributed to establish that the sensing of infected apoptotic cell by dendritic cells is a natural inducer of TH17 cell differentiation. In 2011, he got a tenure researcher position at INSERM, France, and started investigating the metabolic adaptations and mitochondrial biology in innate immune cells and how this contributes to antimicrobial responses. The same year he started as a visiting scientist at CNIC (Centro Nacional de Investigaciones Cardiovasculares) in Madrid, Spain. In 2017, he moved back to France, in Bordeaux and joined the MRGM (Maladies Rares: Génétique et Métabolisme, INSERM U1211). He now continues to investigate the metabolism of host-pathogen interactions at ImmunoConcEpT (University of Bordeaux, CNRS 5164, INSERM 1303) in Bordeaux.
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