Director, Center for Developmental and Regenerative Biology, Cedars-Sinai Guerin Children’s

The host of this seminar is Vincenzo Calvanese.

The Traver laboratory studies the formation and function of hematopoietic stem cells in the early embryo, and how the progeny of these cells provide immunity to the developing animal. Through direct imaging approaches in the zebrafish embryo, the Traver laboratory demonstrated that HSCs derive from the transdifferentiation of hemogenic endothelium comprising the aortic floor. A major goal is to understand the genetic hierarchies that regulate this event. Over the past few years, the Traver group has demonstrated that a variety of signals from the somite are required to instruct HSC fate during the early migration of their shared vascular precursors. Dr. Traver has received a Career Development Award from the National Institutes of Health, a New Faculty Award from the California Institute for Regenerative Medicine, and Scholar Awards from the March of Dimes Foundation, the American Society of Hematology, the Sidney Kimmel Foundation for Cancer Research, and the Leukemia and Lymphoma Society.  Most recently, he was presented the Till & McCulloch Award by the International Society for Experimental Hematology.

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