POSTDOCTORAL RESEARCH - 3D CHROMATIN ORGANIZATION

Reference

PR_BJ_56

Places available

1

Deadline for application

28/08/2021

Requirements

What we need

  • A high level of motivation and interest.
  • PhD degree in molecular biology, genomics, epigenomics, immunology or similar.
  • Expertise, at least, on one of the following areas: B cells, genome organization, gene regulation, epigenetics and single cell omics. We encourage the applications of experimentalist and computational researches.
  • Ability to handle varying workloads and aptitude for teamwork.
  • High level of collaborative and communicative skills.
  • Capacity for analysis and supervision.
  • Good level of English speaking and writing skills (required). Spanish (helpful).

 

What we offer

  • Two years and a half full-funded position. Salary will be adjusted according to the experience of the candidate.
  • An exciting and innovative research project funded by the Human Organs, Physiology, and Engineering (HOPE) programme of the Wellcome Leap (https://wellcomeleap.org/).
  • Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute.
  • Incorporation in a multinational and highly collaborative team.
  • The stimulating environment of the Barcelona metropolitan area.
  • We will provide support and training to prepare competitive fellowship applications (e.g., Marie Curie, EMBO, FEBS, HFSP among others)

  

Main Responsibilities

  • She/he will be part of the multidisciplinary research team of the project “Exhibit B - Engineering human B cells using synthetic biology and tissue engineering” led by Biola M. Javierre.
  • Specifically, she/he will contribute to the generation or analysis of gene regulatory data along in vitro and in vivo B cell differentiation.
  • She/he will supervise students and support grant applications.

Additional Information

Research Description

We are currently seeking for an enthusiastic Postdoctoral Researcher to join the multidisciplinary project “Exhibit B - Engineering human B cells using synthetic biology and tissue engineering”. This project is funded by Wellcome Leap (https://wellcomeleap.org/hope/) and engage four teams: Javierre Team (IJC), Roser Vento-Tormo Team (Wellcome Sanger Institute), Leonardo Morsut Team (University of Southern California) and Kyung-Ho RohTeam  (The University of Alabama in Huntsville).

We are a group of passionate scientists with an insatiable thirst for learning about spatio-temporal organization of the DNA. Our group combines cutting-edge experimental and bioinformatics approaches to understand the specific 3D chromatin organization of haematopoietic cells and its alteration in blood cancers. Our long-term goal is to keep taking steps forwards in the fight against cancer.  We will be unstoppable until we cure it. To do so, we have established a close collaboration with the group lead by Alfonso Valencia, Barcelona Supercomputing Center (https://www.bsc.es/).

This contract is funded by the project Welcome Leap (Hope Program): Exhibit B - Engineering human B cells using synthetic biology and tissue engineering HOPE-2021-2754490174.

 

The main research goals of our lab are:

o   Defining the cell type-specific 3D chromatin organization in human haematopoietic cells.

o   Identifying the altered DNA topology in blood cancer

o   Study non-coding mutations to prioritize new candidate genes and pathways related to blood cancer based

For more information, please contract 3D Chromatin Organization Research Group's webpage (https://www.javierrelab.com/) and the IJC web page (https://www.carrerasresearch.org/en/3d-chromatin-organization_78766).

 

Who we are?

Our mission is to carry out research into the basic, epidemiological, preventive, clinical and translational aspects of leukaemia and other hematologic malignancies.

The vision of the Josep Carreras Leukaemia Research Institute is that research will identify new therapeutic targets and enable us to develop more precise and less aggressive treatments.  We aspire to understand the origin and development of leukaemia and other malignant haematological pathologies in order to be able to prevent them.  We will work for a future in which all leukaemias will be curable.

For further information, please, visit our webpage: http://www.carrerasresearch.org/en and the Josep Carreras non-profit organization: https://www.fcarreras.org/en

The European Commission awarded the IJC the HR Excellence seal in July 2019. The IJC continues to work to maintain its policies in line with the Charter and Code principles.

The HRS4R has the main objective of ensuring that research centers of excellence implement and respect the requirements of the European Charter for Researchers and the Code of Conduct for hiring researchers (from here on referred to as the Charter and Code) within their human resources policies.

This EC initiative aims to promote training, professional development, and mobility for all European scientists.  The IJC supports these values and principles, which will not only serve to strengthen its internal policies but will actively stimulate excellent research and firmly situate the organization as an institution with a stimulating working environment that favors the development of its scientists.

IJC is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, and other legally protected characteristics.

Place of presentation of the candidacies

How to apply

To apply for this opportunity, please send your resume and a cover letter (incl. the contact details of two referees) to jobs@carrerasresearch.orgindicating in the subject of the message: REF.: PR_BJ_56.

 

Deadline for Applications

Please submit your application by the 28th of August, 2021. 

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