In our lab, we focus on both malignant and non-malignant hemopathologies to offer better diagnostics, understand its biological characteristics, and develop new treatments.
We study acute leukemias multi-omics and platelet pathologies like thrombocytopenias, thrombocytopathies and thrombosis.
- Diagnostic activities: morphological, immunophenotyping, cytogenetic and molecular characterization of acute leukaemias).
- Biological characteristics responding to therapy.
- New treatments using cell line models aimed at molecular targets.
- Genomic (microarrays) and proteomic platforms for diagnosis.
- Murine models development.
- Diagnosis and characterization of thrombocytopenia, thrombocytopathies and other platelet pathologies.
- In the framework of the GAIT-2 project (genetic analysis of idiopathic thrombophilia, phase 2), to seek new phenotypes that favor the development of thrombosis, specifically related to the structure and function of platelets and other blood cells.
Through our research, we aim to:
- Consolidate the characterization of hematological tumors and complex, rare, and genetic noncancerous hematopathology’s.
- Include the results of mass-analysis genomic and proteomic platforms in diagnostic algorithms and establish prognostic factors for hematological disorders.
- Develop functional cell culture and animal (murine) models.
- Consolidate cooperation with the GAIT-2 project, especially regarding platelet and other blood cell participation in thrombosis generation.
|Josep Nomdedéu||Group Leaderemail@example.com|