25 January 2019 09:00 - 13:45
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Auditorium, IJC Building

VI IJC Scientific Meeting 2019

This is an internal meeting open only to members of the institute

25 January 2019

Auditorium IJC Campus ICO-GTIP, Badalona

The objective of this internal meeting is to present and discuss ongoing projects from all the IJC campuses. All talks and slides will be in English

Programme

09:00   Welcome: Manel Esteller

Moderators for all sessions will be Manel Esteller, Pablo Menéndez and Francesc Solé

Session I

Short communications (15 minute presentation + 5 minutes questions)

09.10   
Genetics and Epigenetics of Leukemia and Lymphoma
Manel Esteller (Campus ICO-GTIP)

9.30
Plasma C5b9 deposits on endothelium uncover when complement is involved in thrombotic microangiopathy pathogenesis
Júlia Martinez-Sanchez, Campus Clinic

9.50
Polypeptidic nanoparticles for the selective delivery of toxins to CXCR4+ DLBCL cells
Aïda Falgàs, Campus Sant Pau

10.10   Coffee Break

Session II

Short communications (15 minutes presentation + 5 minutes questions)

10.40
Understanding the mechanism of relapse in adult T-cell Acute lymphoblastic leukemia (T-ALL)
Eulalia Genescà, Campus ICO-GTIP

11.00
CRISPR-mediated genome editing of t(4;11)+ in human prenatal and perinatal hematopoietic stem/progenitor cells
Raul Torres/Clara Bueno, Campus Clinic 

11.20
Prognostic impact of the interaction between DNMT3A mutation and internal tandem duplication of the FLT3 gene (FLT3-ITD) in patients with de novo mutated NPM1 (NPM1mut) acute myeloid leukemia
Marta Pratcorona, G. Oñate, M. Hoyos, Campus Sant Pau

11.45     Refreshment

Session III

Short communications (15 minutes presentation + 5 minutes questions)

12.10
Deciphering the role of Polycomb in the three-dimensional constraint of the B cell genome architecture (Preliminary data) Biola Javierre, Campus ICO-GTIP

12.30
The Inducible Caspase-9 switch off system to restrain "on-target off-tumor" toxicities of anti CD123 CAR T-cells in the treatment of AML
Matteo Baroni, Campus Clinic

12.50
CD1A- Directed CAR for relapse/refractory cortical T-ALL and Langerhans Cell Histiocytosis
Diego Sánchez, Campus Clinic

13.10
Multivariable clinical-genetic risk model for predicting venous thromboembolic events in patients with cancer
Joan Carles Souto and Jose Manuel Soria, Campus Sant Pau

13.30
Closing Remarks: Manel Esteller, Evarist Feliu, Pablo Menéndez and Francesc Solé

13.45     Light Buffet Lunch