Auditorium Josep Carreras Leukaemia Research Institute Building Campus Can Ruti Carretera de Can Ruti, Camí de les Escoles s/n 08916 Badalona, Barcelona, Spain

Opening Symposium for the new headquarters of the Josep Carreras Leukaemia Research Institute (IJC)

19-20 September 2019

Genetics and Epigenetics of Leukemia and Lymphoma: From Knowledge to Applications



  • Anna Bigas
  • Marcus Buschbeck
  • Manel Esteller
  • Pablo Menéndez
  • Francesc Solé



Please note that this programme may change. Please see the attached PDF for the most up to date version.


Thursday 19 September

08:30 – 08.55

08:55 – 09:00

09:00 – 09:30
Opening Lecture

Louis Staudt, Center for Cancer Research, National Cancer Institute, NIH, Bethesda
Precision therapy of lymphoma guided by genomic profiling

09.30 – 11.00 
Session 1 - Stem Cells I

Senior lecture 
Pablo Menendez, Josep Carreras Leukaemia Research Institute (IJC) and ICREA, Barcelona
Cell-of-origin and potential immunotherapeutic targets in infant MLL- rearranged B-Cell ALL

Senior lecture
Matthias Merkenschlager, MRC London Institute of Medical Sciences, Imperial College London, London
Gene regulation in 3D

Selected Short talk

11.00 – 11.30 Coffee break

11.30 – 13.15
Session 2 - Stem Cells II

Senior lecture 
Henk Stunnenberg, Radboud University, Nijmegen
Single cell omics in cancer research

Senior lecture 
Veronika Sexl, Institute of Pharmacology and Toxicology, Vienna
CDK6 – at the interface of Rb and p53

Selected Short talk 

13.15 – 15.00 Lunch and Poster Session

15.00 – 16.30             
Session 3 - Genetics I

Senior lecture
Christoph Plass, German Cancer Research Center (DKFZ), Heidelberg
Chromosome 7 abnormalities in AML

Senior lecture 
Jose Angel Martinez-Climent, Center for Applied Medical Research, University of Navarra, Pamplona
A common mechanistic basis of epigenetic drugs to kill cancer cells through immune deregulation of energetic metabolism

Selected Short talk

16.30 – 17.00  Coffee break

17.00 – 18.30         
Session 4 - Genetics II

Senior lecture 
Miguel Angel Piris, Fundación Jimenez Díaz, Madrid
T-cell lymphoma, tumor-stroma interaction 

Senior lecture 
Almudena Ramiro, Spanish National Center for Cardiovascular Research (CNIC), Madrid
Title pending

Selected Short talk

18.30 – 19.30 Poster session, Cocktail and Networking


Friday 20 September

09.00 – 11.00
Session 5 - Epigenetics I

Senior lecture 
Manel Esteller, Josep Carreras Leukaemia Research Institute (IJC), UB and ICREA, Barcelona
Epigenetic contribution to hematological malignancies

Senior lecture 
Ari Melnick, Weill Cornell Medicine, New York
Title pending

Senior lecture 
Anna Bigas, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona
Unravelling the role of beta-catenin in T Acute lymphoblastic leukemia

Selected Short talk

11.00 – 11.30  Coffee break

11.30 – 13.30
Session 6 - Epigenetics II

Senior lecture 
Jonathan Licht, University of Florida Health Cancer Center, Gainesville
Title pending

Senior lecture 
Reiner Siebert, Institute of Human Genetics and Ulm University Medical Center, Ulm
Multi-layer sequence-based OMICs analyses in germinal center B-cell derived lymphomas

Senior lecture 
Thomas Graaf, Centre for Genomic Regulation (CRG), Barcelona
Title pending

Selected Short talk

13.30 – 14.30 Lunch and Poster Session

14.30 – 16.30         
Session 7 - Therapies I

Senior lecture 
Ross Levine, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, NY
Role of mutations in epigenetic regulators in leukemia initiation and maintenance

Senior lecture 
Adolfo Ferrando, Institute for Cancer Genetics, Columbia University, New York
Genetics and mechanisms of acute lymphoblastic leukemia

Senior lecture 
Maria-Victoria Mateos, University Hospital Salamanca, Salamanca
Roadmap to achieve the cure in Myeloma or is the early detection and intervention in Myeloma the way to achieve the cure?

Selected Short talk 

16.30 – 17.00 Coffee break

17.00 – 18.00
Session 8 - Therapies II

Senior lecture 
Felipe Prosper, Center for Applied Medical Research, University of Navarra, Pamplona
The role of epigenetics in the pathogenesis of multiple myeloma

Senior lecture 
Guillermo García-Manero, University of Texas MD Anderson Cancer Center, Houston
Title pending

18.00 – 18.30
Closing Lecture

Michel Sadelain, Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York
New directions in CAR therapy

18.30 – 19.00
Final remarks and Farewell


Download the programme


Information on registration coming soon.  Please watch this space.