IJC Sample Collection for Leukemia and other Hematolgical Diseases

Introduction

The Josep Carreras Leukaemia Research Institute (IJC) Campus ICO-GTP houses the Germans Trias I Pujol Hospital and Institute (IGTP-HUGTP) Biobank Sample Handling Circuit, which manages the processing and storage of voluntarily donated samples of haematological neoplasms.  The samples are stored in the collection entitled “IJC Leukemia and other blood disease Sample Collection’.

The IGTP-HUGTP Biobank Sample Handling Circuit receives the bulk of its samples from the Catalan Institute of Oncology at the Germans Trias i Pujol Hospital (ICO-HUGTP).  Samples received from other hospitals are processed in an identical way. 

All samples in the collection have an attached Informed Consent Form approved by the ICO-HUGTP Ethics Committee and signed by the patient in triplicate, one copy remains at the IJC.  The patient maintains the right to revoke consent at any time and in this case the samples concerned will be destroyed.

Dr Francesc Solé, Scientific Director IJC Campus ICO-GTiP is legally responsible for the collection.  

Working Groups

The Sample Handling Circuit of the IJC currently has the following research lines open:

Myeloid Group
Managers: Dr Francesc Solé, Dr Lurdes Zamora, Dr Blanca Xicoy

Lymphoproliferative Sindromes Group
Mangers: Dr Tomás Navarro, Dr Juan Manuel Sancho

Acute Lymphoid Leukemia Group Grup
Managers: 
Dr osep Maria Ribera, Dr Eulàlia Genescà

Monoclonal Gammapatias Group
Manager: Dr Albert Oriol

The samples received are processed by IJC personnel following the Circuit’s own established protocols. 

Storage of Samples

The IJC provides storage of the samples.  Plasma and serum samples are kept at -80ºC and the isolated cell populations for each sample are cryopreserved in liquid nitrogen tanks at -150ºC.  

The technical staff of the IJC have created a database of patients, donors and samples received and processed according to required specifications for the tracking of each sample in the collection.

The staff verify the quality, security and tracking of the data and samples throughout the process and starting at extraction.   The IJC implements a knowledge management system to document, guarantee tracking and the confidentiality of the registers according to the current legislation (The General Regulation for Data Protection EU Nº 2016/679 (GRDP), the Spanish Organic Law 3/2018 of 5 December for Protection of Personal Data and guarantee of digital rights and rules of development).

The following figures and table show the number of patient samples received by each work group since 2013.

Table 1: Number of samples collected and processed per work group 2014-2017

 

Figure 1: Graph showing samples collected and processed per year 2014-2017